Sorry for the vague question, it was late when I posted.
I should clarify, I'm wanting to run as much as a pump-gas boat will allow - ported, piped (wet, B spec), aftermarket head (pump gas domes as mentioned), MSD/Advent ignition or similar, case porting, maybe stroked?, maybe on bb sleeves? I love a hard-hitting boat, but don't want to buy race gas and I won't run avgas. I am also only going to be running on fresh water (flat).
I've had problems with a race motor in the past, but some of the issues I had may have been as much my fault. But I did 2 top ends in 2 seasons (one of them was a "4-corners" - so that one was my fault). My MSD went out and must have done some damage, as I also needed a new pulser coil - the tech at the bike shop said MSD recommends you keep an extra MSD in your tool box (BS?). Another nearly spoiled day at the lake was saved by Slymo when my starter solenoid failed and the replacement I got from Havasu C&W also failed (salvaged, another mistake). And, it seems like I've read on Group-K's site about crankshafts only lasting a season or 2 on modded boats (though I know opinions on the "matter-of-factness" of Klemm's recommendations vary).
Thanks in advance, I know this is a broad, somewhat subjective question - I just want to know what some of your experiences are. The amount of money my Superjet required for maintenance was too high for me but may have been easier to swallow if I was prepared for it (saving $$) - however that cost may also have been offset somewhat due to it being a tired old raceboat.