The only single intake that works well overall on the 750 is a PJS. It has smaller passages than stock and designed for a keihin. I have adapted a 46 to a stock manifold with mixed results. The jetting that gave best response was too lean for long WOT runs. The big mikuni on a stock manifold had a little better pop than my Keihin 42 on the pjs manifold but would lean out. Save big singles for jumping and smaller 42-44s for full throttle runs.