cryptosporidiosis

cosander

Dallas/Fort worth
anybody worry about this while @ the lake? seems we are having an outbreak here in texas
 

Swooperjet

Bring the brap!!
Location
Dallas, TX
I was worried a little bit since they'd just had the outbreaks around Ft. Worth sinceit's so close...but untill I get sick or they start reporting it in the two lakes I ride, I try not to hassle it.:thinking:
 
not a concern here but i do worry about those huge portugese man-o-war jelly fish i see around me sometimes..those suckers are way bigger than i care to find out with physical contact.. depending on tide and weather you get "clouds" of them in here...riding along then you see nothing but purple mushroom looking things in the water..

instantly brings on the " please dont crash here...please dont crash here" mentality..lol

had a couple seals get real close and curious, but i worry more about the killer whale thats hunting those seals.

ahhhh....the joys of the oceans.. ;)
 

Odd Duck

Jet Vet
Location
DFW, TX
The one that freaks me out is the amoeba thing that killed the kid in Havasu this year. Very rare though.

Yeah, while crypto causes a nasty infection with potential for explosive diarrhea, it is at least treatable. The ameoba is not treatable. Once that little parasite is in your brain, you're done for.
 

ski4

gonzo
Location
cleveland
There is no reliable therapy for cryptosporidiosis . Recovery from Cryptosporidium infection depends largely upon the immune status of the host
 

Odd Duck

Jet Vet
Location
DFW, TX
There is no reliable therapy for cryptosporidiosis . Recovery from Cryptosporidium infection depends largely upon the immune status of the host

This is true of almost any infection/infestation. If the host immune system is sufficiently compromised, there is virtually nothing that will completely clear with only medication. Even relatively simple, non-resistant organisms will return if the immune system is completely shot. The immune system has to be doing SOMETHING to help. It doesn't always have to do a lot, but it has to, at the least, clear out the medication weakened organisms.
 

ski4

gonzo
Location
cleveland
of course
but this is a parasite so routine atb's are not of benefit
however there is some indication that clindamycin is effective as prophylaxis 75% of the time
they don't know why

only children and hiv pt's get any treatment though normally and they usually relapse even with treatment
 

DAG

Yes, my balls tickled from that landing
Location
Charlotte, NC
i love wiki... lol -.-
"infection can cause permanent and life-threatening explosive diarrhea also known as "Thai Fourth of July"."

:lol:
 

Odd Duck

Jet Vet
Location
DFW, TX
of course
but this is a parasite so routine atb's are not of benefit
however there is some indication that clindamycin is effective as prophylaxis 75% of the time
they don't know why

only children and hiv pt's get any treatment though normally and they usually relapse even with treatment

Interesting. We usually treat animals when they have it, primarily supportive care, but also with meds, usually Tylosin (cheap and easy to find) or Paramomycin (I've never used this one).

I suspect animals whose symptoms remain long enough to need treatment are partially immune compromised and need a little help.
 

3wheelerdude

Talk less, Ride more!
Location
Ontario Canada
I got a crypto last year and it sucks. It took a week out of my riding season but no biggie.
You have to ingest infected water in order to get it, so keep your mouth closed and you should be fine.
 

ski4

gonzo
Location
cleveland
Interesting. We usually treat animals when they have it, primarily supportive care, but also with meds, usually Tylosin (cheap and easy to find) or Paramomycin (I've never used this one).

I suspect animals whose symptoms remain long enough to need treatment are partially immune compromised and need a little help.

yeah those sound familiar for human use too
again inthe immunocomprimised
but in the general population it's just supportive care and let the body beat it up

i still would like to know why clinda can work prophylacticly given that it's a parasite?????
 

Odd Duck

Jet Vet
Location
DFW, TX
yeah those sound familiar for human use too
again inthe immunocomprimised
but in the general population it's just supportive care and let the body beat it up

i still would like to know why clinda can work prophylacticly given that it's a parasite?????

Most of the treatments for one-celled intestinal parasites, including flagellated organisms, are antibiotics. Remember, a lot of the antibiotics work by inhibiting cell wall or cell membrane formation, or interfering with ion pumps, etc, which is fairly universal in cells of most any species - bacteria to human and all in between. The parasites or the bacteria just live faster, so they die faster (before the drug reaches toxic level in people/animals).

All drugs (medicines) are poisons. It's just a matter of finding doses that have tolerable/minimal side effects to the host while killing or inhibiting growth of the parasite/bacteria/virus, etc. Some drugs have wide (sometimes huge) safety margins, some have very narrow safety margins.

For instance, cancer chemotherapy drugs often have narrow safety margins (hence the high rate of side-effects) since they are trying to kill abnormal cells that are actually a part of the host. Most antibiotics and antiparasitic drugs have wider safety margins since they are trying to kill organisms that are not inherently part of the host, therefore drugs can be selected more easily that have lower side-effect on the host species and a greater effect on the target organism.

This same effect can bite vets in the arse if they're treating species that have very little information known about how drugs work in them. A drug that is perfectly safe in one species can be highly toxic to another species. I could give you a list, but that would get boring really fast (even for those that aren't bored already).
 
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